SELECT 
  cscart_product_prices.product_id, 
  MIN(
    IF(
      cscart_product_prices.percentage_discount = 0, 
      cscart_product_prices.price, 
      cscart_product_prices.price - (
        cscart_product_prices.price * cscart_product_prices.percentage_discount
      )/ 100
    )
  ) AS price 
FROM 
  cscart_product_prices 
WHERE 
  cscart_product_prices.product_id IN (
    65535, 65674, 65465, 65418, 65536, 65423, 
    65455, 65700, 65453, 65625, 64815, 
    65691
  ) 
  AND cscart_product_prices.lower_limit = 1 
  AND cscart_product_prices.usergroup_id IN (0, 1) 
GROUP BY 
  cscart_product_prices.product_id

Query time 0.00086

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "table_name": "cscart_product_prices",
      "access_type": "range",
      "possible_keys": ["usergroup", "product_id", "lower_limit", "usergroup_id"],
      "key": "product_id",
      "key_length": "9",
      "used_key_parts": ["product_id", "usergroup_id", "lower_limit"],
      "rowid_filter": {
        "range": {
          "key": "lower_limit",
          "used_key_parts": ["lower_limit", "product_id", "usergroup_id"]
        },
        "rows": 24,
        "selectivity_pct": 0.889547813
      },
      "rows": 24,
      "filtered": 100,
      "index_condition": "cscart_product_prices.lower_limit = 1 and cscart_product_prices.product_id in (65535,65674,65465,65418,65536,65423,65455,65700,65453,65625,64815,65691) and cscart_product_prices.usergroup_id in (0,1)"
    }
  }
}

Result

product_id price
64815 73.000000
65418 259.000000
65423 230.000000
65453 275.000000
65455 265.000000
65465 295.000000
65535 330.000000
65536 325.000000
65625 135.000000
65674 355.000000
65691 185.000000
65700 155.000000