SELECT 
  cscart_product_prices.product_id, 
  MIN(
    IF(
      cscart_product_prices.percentage_discount = 0, 
      cscart_product_prices.price, 
      cscart_product_prices.price - (
        cscart_product_prices.price * cscart_product_prices.percentage_discount
      )/ 100
    )
  ) AS price 
FROM 
  cscart_product_prices 
WHERE 
  cscart_product_prices.product_id IN (
    65424, 65650, 65681, 60738, 65793, 62671, 
    64340, 61386, 65672, 65425, 65300, 
    65534
  ) 
  AND cscart_product_prices.lower_limit = 1 
  AND cscart_product_prices.usergroup_id IN (0, 1) 
GROUP BY 
  cscart_product_prices.product_id

Query time 0.00091

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "table_name": "cscart_product_prices",
      "access_type": "range",
      "possible_keys": ["usergroup", "product_id", "lower_limit", "usergroup_id"],
      "key": "product_id",
      "key_length": "9",
      "used_key_parts": ["product_id", "usergroup_id", "lower_limit"],
      "rowid_filter": {
        "range": {
          "key": "lower_limit",
          "used_key_parts": ["lower_limit", "product_id", "usergroup_id"]
        },
        "rows": 24,
        "selectivity_pct": 0.889547813
      },
      "rows": 24,
      "filtered": 100,
      "index_condition": "cscart_product_prices.lower_limit = 1 and cscart_product_prices.product_id in (65424,65650,65681,60738,65793,62671,64340,61386,65672,65425,65300,65534) and cscart_product_prices.usergroup_id in (0,1)"
    }
  }
}

Result

product_id price
60738 181.000000
61386 126.000000
62671 44.000000
64340 350.000000
65300 220.000000
65424 275.000000
65425 225.000000
65534 335.000000
65650 314.000000
65672 314.000000
65681 660.000000
65793 1049.000000